Lab Members

The lab is a collegial and enthusiastic environment.  Students participate in weekly lab meeting and monthly journal club and acquire analytical and presentation skills.  There is also a bi-weekly joint lab meeting among all the labs on the floor, giving the student the opportunity to present their work to (and learn from) a multidisciplinary audience. Dr. Lee makes mentorship and education of students and fellows a top priority.

Changsen Wang, Lab Manager
 
 
Siavash GhaffariPhD - Post-doctoral fellow

I completed my PhD program at the McGill University School of Engineering, studying the role of in vivo flow dynamics on angiogenesis during embryonic vascular development. Currently, my research focuses on the investigation of the molecular mechanisms of low density lipoprotein transcytosis across human coronary artery endothelial cells.
 
 
Karen FungPhD Candidate

I completed my M.Sc. thesis in August of 2014 with Dr. Trimble at Sick Kids looking at the role of the adaptor proteins Cin85 and CD2AP in septin-mediated cytokinesis in mammalian cells. I am currently in the PhD program at the Biochemistry department at the University of Toronto and am co-supervised by Dr. Lee and Dr. Fairn. My project involves the investigation of the molecular mechanisms of high density lipoprotein transcytosis across the blood brain barrier. By understanding how this occurs we hope to translate these findings to a therapeutic setting to improve drug delivery to the brain. 
 
 
Victoria Mintsopoulos, MSc Candidate

I completed my undergraduate degree at Queen’s University in Life Sciences. My fourth year undergraduate thesis focused on the effect of IL-27 on endotoxin tolerance and LPS-binding in human macrophages and monocytes. I joined Dr. Lee’s lab in 2017 as a M.Sc. student in the Institute of Medical Science. My research focuses on the molecular mechanisms of endothelial leakage and potential treatments in acute lung injury.






Rajiv Sanwal, MSc Candidate

I completed my undergraduate degree in pathology at the University of Western Ontario. For my undergraduate thesis, I characterized a novel transgenic mouse model to better study a rare intestinal epithelial cell population called tuft cells. I am enrolled in Laboratory Medicine and Pathobiology and I am currently working on understanding the effect of cardiovascular risk factors on LDL transcytosis.


 
 


Negar Khosraviani, MSc Candidate

I completed my undergraduate degree at the University of Toronto in Pathobiology and Immunology.  My fourth year undergraduate thesis project focused on the role of miR-130b-3p on VLDL production and secretion, and on formation of lipid droplets.  I will be completing my Master's in the department of Laboratory Medicine and Pathobiology.  My project will focus on the mechanism of albumin transcytosis across dermal endothelial cells. 




Elyse Latreille, MSc Candidate

I completed my undergraduate degree at the University of Ottawa in Biology.  My undergraduate thesis focused on the role of autophagy in breast cancer invasion and metastasis. Before joining Dr. Lee's lab in 2018, I worked in a virology lab, investigating the role of lipid mediators in Zika virus infection of neural progenitor cells. I am currently enrolled as a M.Sc. student in the department of Laboratory Medicine and Pathobiology. My project aims to identify and characterize the mechanisms of action of novel therapies for severe influenza infections. 





Misha Ditmans, MASc Candidate (Ryerson University)

I completed my undergraduate degree in Biomedical Sciences at York University. I am currently enrolled as a MASc student in Biomedical Engineering at Ryerson University. My project seeks to optimize the use of ultrasound and microbubbles in the treatment of acute lung injury.

Erika Jang, MSc candidate

I completed my undergraduate degree in Biotechnology at the University of British Columbia. Before Joining Dr. Lee's lab, I studied the signaling pathways involved in myocarditis and identified potential biomarkers for the disease. I am currently a Master's student in Laboratory Medicine and Pathobiology at the University of Toronto.  My project focuses on HDL and LDL transcytosis by endothelial cells.

Undergraduate Students:
 Farnoosh Naderi Nabi, Madelene Abramian, Nikki Zamani Farahani 

Lab alumni (partial): Hira Raheel (MSc), Michael Sugiyama (PhD), Elizabeth Sabath (PDF), Victoria Tokarz (MSc), Sha (Lucy) Guan (MSc), Susan Armstrong (MD/PhD); Paymon Azizi (MSc); Asela Gamage (MSc); Vahid Khajoee (PDF). Many alumni have gone on to post-doctoral fellowships, medical school, graduate school, or combined MD/PhD training.